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AKA-188
Maytansine
Cat. No.
AKA-188
CAS No.
35846-53-8
MF
C34H46ClN3O10
MW
692.2
Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest at subnanomolar concentrations.
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Storage and Shipping
References
Product Name
Maytansine
CAS No.
35846-53-8
MF
C34H46ClN3O10
MW
692.2
Specification
98%
Description
Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest at subnanomolar concentrations. Packing: 10mg, 20mg, 50mg, 100mg, 500mg, 1g, 5g, 10g, 1kg Availability: Under Development (current pilot scale, validation production in 3-4 month, DMF filing in 12 month)
Documents
Certificate of Analysis (COA), API specification, Safety Data Sheet (SDS/MSDS), evidence of GMP compliance, Stability data / Stability summary, etc.
Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Lopus M, et al. Maytansine and cellular metabolites of antibody-maytansinoid conjugates strongly suppress microtubule dynamics by binding to microtubules. Molecular Cancer Therapeutics. 2010;9(10):2689-2699.
[2]. Remillard S, et al. Antimitotic activity of the potent tumor inhibitor maytansine. Science. 1975;189(4207):1002-1005.
[2]. Remillard S, et al. Antimitotic activity of the potent tumor inhibitor maytansine. Science. 1975;189(4207):1002-1005.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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* Some statements have not been evaluated by national authorities. * Some products are not intended to diagnose, treat, cure, or prevent any disease. * For literature supporting, please contact us directly.